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Comprehensive assessment of hypertensive heart disease: cardiac magnetic resonance in focus

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单位: [1]Univ Hosp Dr Dragisa Misovic Dedinje, Dept Cardiol, Heroja Milana Tepica 1, Belgrade 11000, Serbia [2]Univ Milano Bicocca, Milan, Italy [3]Ist Auxol Italiano, Clin Res Unit, Viale Resistenza 23, I-20036 Meda, Italy [4]Univ Leeds, Leeds Inst Cardiovasc & Metab Med, Dept Biomed Imaging Sci, Leeds, W Yorkshire, England [5]Clin Ctr Serbia, Ctr Nucl Med, Belgrade, Serbia [6]Univ Belgrade, Fac Med, Belgrade, Serbia [7]Huazhong Univ Sci & Technol, Dept Internal Med, Tongji Hosp, Div Cardiol,Tongji Med Coll, Wuhan 430030, Peoples R China [8]Hubei Key Lab Genet & Mol Mech Cardiol Disorders, Wuhan 430030, Hubei, Peoples R China [9]Policlin Monza, Monza, Italy
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关键词: Left ventricle Cardiac magnetic resonance Strain Late gadolinium enhancement T1 mapping

摘要:
Arterial hypertension represents the most frequent cardiovascular risk factor that is associated with cardiac remodeling. Hypertensive heart disease was defined by the presence of left ventricular hypertrophy (LVH) and diastolic dysfunction, and it has been diagnosed by echocardiography in everyday clinical practice. Interstitial myocardial fibrosis is the underlying cause of hypertension-induced cardiac remodeling, and it could not be visualized with different echocardiographic methods. Cardiac magnetic resonance (CMR) and its methods such as late gadolinium enhancement, and T1 mapping provides qualitative and quantitative assessment of interstitial myocardial fibrosis in hypertensive patients. Furthermore, CMR can provide differentiation of LVH between hypertensive patients and cardiomyopathies (hypertrophic or Fabry disease). Timely diagnosis of cardiac impairment and early treatment is essential because regression of LVH could be achieved with adequate treatment. Diffuse cardiac fibrosis in hypertensive patients might be an underlying mechanism that explains the increased cardiovascular morbidity and mortality in this population. Future longitudinal investigations are necessary to determine causal relationship between diffuse fibrosis and cardiovascular outcome in these patients. The aim of this review is to summarize the current knowledge regarding CMR techniques and their potential usage in patients with hypertensive heart disease.

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出版当年[2020]版
大类 | 2 区 医学
小类 | 3 区 心脏和心血管系统
最新[2025]版
大类 | 2 区 医学
小类 | 3 区 心脏和心血管系统
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出版当年[2019]版:
Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
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Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

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第一作者单位: [1]Univ Hosp Dr Dragisa Misovic Dedinje, Dept Cardiol, Heroja Milana Tepica 1, Belgrade 11000, Serbia
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