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Discrepancies Between Two Automated Immunoassay Systems in Determining Hepatitis B Virus Markers in Serum Samples with Concomitant Presence of Antigens and Antibodies

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单位: [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Lab Med, Tongji Hosp, Wuhan 430030, Peoples R China [*1]Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Lab Med, 1095 Jiefang Ave, Wuhan 430030, Peoples R China
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关键词: hepatitis B viral markers HBsAg HBeAg anti-HBs anti-HBe

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This study compared the assay results of HBV markers obtained with two automated immunoassay systems in serum samples with concomitant HBV antigens and antibodies. Eighty-nine samples of concomitant HBsAg and anti-HBs and 74 samples of concomitant HBeAg and anti-HBe were analyzed by the Abbott Architect i2000 and the Roche Elecsys 2010 immunoassay systems. The overall concordance rates of the Architect and Elecsys results were 78.6% for samples with concomitant HBsAg and anti-HBs and 77% for samples with concomitant HBeAg and anti-HBe. The data show that substantial differences exist between the results obtained by these two systems, especially in determining anti-HBs and HBeAg at low concentrations.

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出版当年[2009]版:
大类 | 4 区 医学
小类 | 4 区 医学实验技术
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 医学实验技术
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出版当年[2008]版:
Q3 MEDICAL LABORATORY TECHNOLOGY
最新[2023]版:
Q3 MEDICAL LABORATORY TECHNOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2008版] 出版当年五年平均 出版前一年[2007版] 出版后一年[2009版]

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第一作者单位: [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Lab Med, Tongji Hosp, Wuhan 430030, Peoples R China
通讯机构: [*1]Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Lab Med, 1095 Jiefang Ave, Wuhan 430030, Peoples R China
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