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Review on Regulation of Inwardly Rectifying Potassium Channels

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收录情况： ◇ SCIE

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单位： [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Infect Dis, Tongji Hosp, Wuhan 430030, Peoples R China

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关键词： Inwardly rectifying potassium channel Kir structure molecular determinant regulatory factor

摘要：

An inwardly rectifying potassium channel (Kir) is a kind of protein complex that is widely expressed on excitable and nonexcitable cell membranes. Kir channels serve important roles in cellular physiology such as cell excitability and K+ homeostasis. The Kirs (KIR1-7) are regulated by many factors: phosphatidylinosital-4, 5-bisphosphate (PIP2), ATP, or G-proteins. Other factors like polyamines, kinases, pH, and Na+ ions act cooperatively to modulate Kir channels. Different types and specific distributions of KIR channels determine the diversity of regulatory mechanisms. This review provides insight into Kir channel regulation.

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出版当年[2010]版：

大类 | 3 区生物

小类 | 3 区生物工程与应用微生物 4 区遗传学

最新[2025]版：

大类 | 4 区医学

小类 | 4 区生物工程与应用微生物 4 区遗传学

JCR分区：

出版当年[2009]版：

Q2 GENETICS & HEREDITY Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

最新[2023]版：

Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Q4 GENETICS & HEREDITY

影响因子： 1.5 最新[2023版] 1.9 最新五年平均 2.949 出版当年[2009版] 2.83 出版当年五年平均 1.947 出版前一年[2008版] 4.111 出版后一年[2010版]

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第一作者单位： [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Infect Dis, Tongji Hosp, Wuhan 430030, Peoples R China

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通讯机构： [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Infect Dis, Tongji Hosp, Wuhan 430030, Peoples R China [*1]Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Infect Dis, Tongji Hosp, 1095 Jiefang Aye, Wuhan 430030, Peoples R China

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