Background and Purpose Fever is a common symptom of acute aortic dissection. The beginning time and duration of fever after percutaneous endovascular stent-graft in patients with aortic dissection is not well known. The present study was undertaken to investigate the characteristics of fever after percutaneous endovascular stent-graft in patients with type B aortic dissection. Methods and Results In this retrospective study the data of a total of 64 patients with type B acute aortic dissection undergoing percutaneous endovascular stent-graft were collected and analyzed. In total, 55 patients (85.9%) had fever after stent-graft. The time of fever onset was during the initial 2 days after interventional procedure (92.7%), and the duration of fever of most patients was not beyond 7 days after stent implantation. The fever before stent implantation was associated with the beginning time of fever after stent implantation, but not with the duration of fever. Conclusion The results of this study could provide important reference information for the evaluation of fever before and after interventional treatment in patients with acute aortic dissection.