Liver tumor, one of the most wide-spread diseases, has a very high mortality in China. To improve success rates of liver surgeries and life qualities of such patients, we implement an interactive liver surgery planning system based on contrast-enhanced liver CT images. The system consists of five modules: pre-processing, segmentation, modeling, quantitative analysis and surgery simulation. The Graph Cuts method is utilized to automatically segment the liver based on an anatomical prior knowledge that liver is the biggest organ and has almost homogeneous gray value. The system supports users to build patient-specific liver segment and sub-segment models using interactive portal vein branch labeling, and to perform anatomical resection simulation. It also provides several tools to simulate atypical resection, including resection plane, sphere and curved surface. To match actual surgery resections well and simulate the process flexibly, we extend our work to develop a virtual scalpel model and simulate the scalpel movement in the hepatic tissue using multi-plane continuous resection. In addition, the quantitative analysis module makes it possible to assess the risk of a liver surgery. The preliminary results show that the system has the potential to offer an accurate 3D delineation of the liver anatomy, as well as the tumors' location in relation to vessels, and to facilitate liver resection surgeries. Furthermore, we are testing the system in a full-scale clinical trial.
基金:
National High Technology Research and Development Program of China (863 Program)National High Technology Research and Development Program of China [2006AA02Z333]; Natural Science Foundation of China (NSFC),National Natural Science Foundation of China (NSFC) [61027006]; Ministry of Science and Technology of China (MOST)Ministry of Science and Technology, China [2009DFR30580]; Research Fund for the Doctoral Program of Higher Education of ChinaResearch Fund for the Doctoral Program of Higher Education of China (RFDP)Specialized Research Fund for the Doctoral Program of Higher Education (SRFDP) [20090142110068]
语种:
外文
被引次数:
WOS:
第一作者:
第一作者单位:[1]Wuhan Natl Lab Optoelect, Wuhan, Peoples R China[2]Huazhong Univ Sci & Technol, Dept Biomed Engn, Wuhan, Peoples R China
通讯作者:
通讯机构:[1]Wuhan Natl Lab Optoelect, Wuhan, Peoples R China[2]Huazhong Univ Sci & Technol, Dept Biomed Engn, Wuhan, Peoples R China
推荐引用方式(GB/T 7714):
Wang Luyao,Liu Jingjing,Yuan Rong,et al.Implementation of an Interactive Liver Surgery Planning System[J].MEDICAL IMAGING 2011: VISUALIZATION, IMAGE-GUIDED PROCEDURES, AND MODELING.2011,7964:doi:10.1117/12.878461.
APA:
Wang, Luyao,Liu, Jingjing,Yuan, Rong,Gu, Shuguo,Yu, Long...&Hu, Daoyu.(2011).Implementation of an Interactive Liver Surgery Planning System.MEDICAL IMAGING 2011: VISUALIZATION, IMAGE-GUIDED PROCEDURES, AND MODELING,7964,
MLA:
Wang, Luyao,et al."Implementation of an Interactive Liver Surgery Planning System".MEDICAL IMAGING 2011: VISUALIZATION, IMAGE-GUIDED PROCEDURES, AND MODELING 7964.(2011)