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New diagnostic criteria and severity assessment of acute cholecystitis in revised Tokyo guidelines

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单位: [1]Nagoya Daini Red Cross Hosp, Showa Ku, Nagoya, Aichi 4668650, Japan [2]Teikyo Univ, Sch Med, Dept Surg, Tokyo 173, Japan [3]Washington Univ, Sect Hepatobiliary & Pancreat Surg, St Louis Sch Med, St Louis, MO USA [4]Univ Cincinnati, Coll Med, Dept Surg, Cincinnati, OH 45267 USA [5]Ichinomiya Municipal Hosp, Dept Emergency & Crit Care Med, Ichinomiya, Japan [6]Jichi Med Univ, Ctr Clin Infect Dis, Mibu, Tochigi, Japan [7]Indiana Univ Sch Med, Dept Surg, Indianapolis, IN USA [8]Univ Amsterdam, Acad Med Ctr, Dept Surg, NL-1105 AZ Amsterdam, Netherlands [9]Univ Edinburgh, Edinburgh, Midlothian, Scotland [10]Heidelberg Univ, Dept Surg, D-6900 Heidelberg, Germany [11]Ogaki Municipal Hosp, Dept Gastroenterol, Ogaki, Japan [12]Sapporo Med Univ, Dept Surg Oncol & Gastroenterol Surg, Sch Med, Sapporo, Hokkaido, Japan [13]Chiba Univ, Dept Med & Clin Oncol, Grad Sch Med, Chiba, Japan [14]Tokyo Med Univ, Dept Gastroenterol & Hepatol, Tokyo, Japan [15]Int Univ Hlth & Welf, Clin Res Ctr, Kaken Hosp, Ichikawa, Japan [16]Fukuoka Univ, Sch Med, Dept Surg Gastroenterol, Fukuoka 81401, Japan [17]Kitakyushu Municipal Yahata Hosp, Dept Surg, Kitakyushu, Fukuoka, Japan [18]Kanazawa Univ, Dept Radiol, Grad Sch Med Sci, Kanazawa, Ishikawa, Japan [19]Kawasaki Med Sch, Dept Endoscopy & Ultrasound, Okayama, Japan [20]Tokyo Womens Med Univ, Dept Surg, Inst Gastroenterol, Tokyo, Japan [21]Univ Auckland, Dept Surg, Auckland 1, New Zealand [22]Univ Cape Town, Div Gen Surg, ZA-7925 Cape Town, South Africa [23]Univ Hong Kong, Dept Surg, Queen Mary Hosp, Hong Kong, Hong Kong, Peoples R China [24]Hosp Selayang, Dept Hepatopancreatobiliary Surg, Kuala Lumpur, Malaysia [25]Univ Buenos Aires, Dept Surg, Hosp Italianio, Buenos Aires, DF, Argentina [26]Univ Occupat & Environm Hlth, Sch Med, Dept Prevent Med & Community Hlth, Kitakyushu, Fukuoka 807, Japan [27]Toho Univ, Dept Surg, Med Ctr, Ohashi Hosp, Tokyo, Japan [28]Huazhong Univ Sci & Technol, Hepat Surg Ctr, Dept Surg, Tongi Med Coll,Tongji Hosp, Wuhan 430074, Peoples R China [29]Lilavati Hosp & Res Ctr, Dept Surg Oncol, Bombay, Maharashtra, India [30]Univ Ulsan, Asan Med Ctr, Ulsan 680749, South Korea [31]Flinders Med Ctr, Div Surg & Specialty Serv, Adelaide, SA, Australia [32]Chang Gung Univ, Chang Gung Mem Hosp, Tao Yuan, Taiwan
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关键词: Acute cholecystitis Murphy's sign Diagnostic criteria Severity assessment Guidelines

摘要:
Background The Tokyo Guidelines for the management of acute cholangitis and cholecystitis (TG07) were published in 2007 as the world's first guidelines for acute cholangitis and cholecystitis. The diagnostic criteria and severity assessment of acute cholecystitis have since been widely used all over the world. A validation study of TG07 has shown that the diagnostic criteria for acute cholecystitis are highly reliable but that the definition of definite diagnosis is ambiguous. In addition, considerable new evidence referring to acute cholecystitis as well as evaluations of TG07 have been published. Consequently, we organized the Tokyo Guidelines Revision Committee to evaluate TG07, recognize new evidence, and conduct a multi-center analysis to revise the guidelines (TG13). Methods and materials We retrospectively analyzed 451 patients with acute cholecystitis from multiple tertiary care centers in Japan. All 451 patients were first evaluated using the criteria in TG07. The "gold standard" for acute cholecystitis in this study was a diagnosis by pathology. The validity of TG07 diagnostic criteria was investigated by comparing clinical with pathological diagnosis. Results Of 451 patients evaluated, a total of 227 patients were given a diagnosis of acute cholecystitis by pathological examination (prevalence 50.3 %). TG07 criteria provided a definite diagnosis of acute cholecystitis in 224 patients. The sensitivity of TG07 diagnostic criteria for acute cholecystitis was 92.1 %, and the specificity was 93.3 %. Based on the preliminary results, new diagnostic criteria for acute cholecystitis were proposed. Using the new criteria, the sensitivity of definite diagnosis was 91.2 %, and the specificity was 96.9 %. The accuracy rate was improved from 92.7 to 94.0 %. In regard to severity grading among 227 patients, 111 patients were classified as Mild (Grade I), 104 as Moderate (Grade II), and 12 as Severe (Grade III). Conclusion The proposed new diagnostic criteria achieved better performance than the diagnostic criteria in TG07. Therefore, the proposed criteria have been adopted as new diagnostic criteria for acute cholecystitis and are referred to as the 2013 Tokyo Guidelines (TG13). Regarding severity assessment, no new evidence was found to suggest that the criteria in TG07 needed major adjustment. As a result, TG07 severity assessment criteria have been adopted in TG13 with minor changes.

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出版当年[2011]版:
大类 | 4 区 医学
小类 | 4 区 胃肠肝病学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 胃肠肝病学 3 区 外科
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出版当年[2010]版:
Q3 GASTROENTEROLOGY & HEPATOLOGY
最新[2023]版:
Q1 SURGERY Q2 GASTROENTEROLOGY & HEPATOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2010版] 出版当年五年平均 出版前一年[2009版] 出版后一年[2011版]

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第一作者单位: [1]Nagoya Daini Red Cross Hosp, Showa Ku, Nagoya, Aichi 4668650, Japan [*1]Nagoya Daini Red Cross Hosp, Showa Ku, 2-9 Myoken Cho, Nagoya, Aichi 4668650, Japan
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通讯机构: [1]Nagoya Daini Red Cross Hosp, Showa Ku, Nagoya, Aichi 4668650, Japan [*1]Nagoya Daini Red Cross Hosp, Showa Ku, 2-9 Myoken Cho, Nagoya, Aichi 4668650, Japan
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