单位：[1]Peking Union Med Coll Hosp, Med Intens Care Unit, Beijing, Peoples R China[2]Peking Univ Peoples Hosp, Dept Crit Care Med, Beijing, Peoples R China[3]Sichuan Univ, Dept Crit Care Med, W China Hosp, Chengdu 610064, Peoples R China四川大学华西医院[4]Xinjiang Med Univ, Affiliated Hosp 1, Dept Crit Care Med, Urumqi, Peoples R China[5]Harbin Med Univ, Affiliated Hosp 1, Dept Crit Care Med, Harbin, Peoples R China[6]China Med Univ, Affiliated Hosp 1, Dept Crit Care Med, Shenyang, Peoples R China[7]Cent S Univ, Xiangya Hosp, Dept Crit Care Med, Changsha 410083, Hunan, Peoples R China[8]Capital Med Univ, Beijing Tongren Hosp, Dept Crit Care Med, Beijing, Peoples R China首都医科大学附属北京同仁医院首都医科大学附属同仁医院[9]Jilin Univ, Hosp 2, Dept Emergency & Crit Care Med, Changchun 130023, Peoples R China[10]Kunming Med Coll, Affiliated Hosp 1, Dept Emergency Med, Kunming, Peoples R China昆明医科大学附属第一医院[11]Shandong Univ, Qilu Hosp, Dept Crit Care Med, Jinan 250100, Peoples R China[12]Zhejiang Prov Peoples Hosp, Dept Crit Care Med, Hangzhou, Zhejiang, Peoples R China[13]Huazhong Univ Sci & Technol,Tongji Hosp,Dept Crit Care Med,Tongji Med Coll,Wuhan 430074,Peoples R China华中科技大学同济医学院附属同济医院急诊医学科[14]Hebei Med Univ Fourth Hosp, Dept Crit Care Med, Shijiazhuang, Peoples R China河北医科大学第四医院[15]Ningxia Med Univ, Affiliated Hosp, Dept Crit Care Med, Yinchuan, Peoples R China[16]Chongqing Med Univ, Affiliated Hosp 1, Dept Crit Care Med, Chongqing, Peoples R China重庆医科大学附属第一医院[17]Capital Med Univ, Fuzing Hosp, Dept Crit Care Med, Beijing, Peoples R China[18]Fujian Med Univ, Affiliated Hosp 1, Dept Crit Care Med, Fuzhou, Peoples R China[19]Shanghai Jiao Tong Univ, Ruijin Hosp, Dept Emergency Med, Shanghai 200030, Peoples R China[20]Guangdong Gen Hosp, Dept Crit Care Med, Guangzhou, Guangdong, Peoples R China广东省人民医院[21]Hainan Prov Peoples Hosp, Dept Crit Care Med, Haikou, Peoples R China[22]Inner Mongolia Med Coll, Affiliated Hosp, Dept Crit Care Med, Hohhot, Peoples R China
Objectives: We sought to describe the demographics, case mix, interventions, and clinical outcome of critically ill patients admitted to ICUs in Mainland China. Design: A 2-month (July 1, 2009, to August 31, 2009) prospective, observational cohort study. Setting: Twenty-two ICUs in Mainland China. Patients: Adult patients admitted to participating ICUs during the study period with an ICU length of stay >24 hrs. Interventions: None. Measurements and Main Results: Patient characteristics, including demographics, underlying diseases, severity of illness, admission status, complications, intervention and treatment during ICU stay, and clinical outcome were recorded in case report form. The primary outcome measure was all-cause hospital mortality. Independent predictors for hospital mortality were determined with multivariate logistic regression analysis. One thousand two hundred ninety-seven patients met the inclusion criteria for the study, 821 (63.3%) were male, and mean age was 58.5 +/- 19.2 yrs. Mean Acute Physiology and Chronic Health Evaluation II score was 18.0 +/- 8.1, and mean Sequential Organ Failure Assessment score was 65 +/- 3.8. One third of the patients were postoperative ICU admissions. Seven hundred sixty-five patients (59.0%) developed infections, followed by severe sepsis or septic shock (484, 37.3%), acute kidney injury (398, 30.7%), and acute lung injury/acute respiratory distress syndrome (351, 27.1%). Mechanical ventilation was used in almost three fourths of the patients, whereas any type of renal replacement therapy was used in 173 patients (13.3%). Hospital mortality was 20.3%. Multivariate logistic regression analysis found that Acute Physiology and Chronic Health Evaluation II score, solid tumor, severe sepsis/septic shock, acute lung injury/acute respiratory distress syndrome, and acute kidney injury were independent risk factors for hospital mortality. Conclusions: Critically ill patients in ICUs in Mainland China exhibited a case mix similar to those of Western countries, although there are significant differences in intensive care unit admission rates and disease severity between Western and Chinese ICUs. (Crit Care Med 2013; 41:84-92)
第一作者单位：[1]Peking Union Med Coll Hosp, Med Intens Care Unit, Beijing, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Du Bin,An Youzhong,Kang Yan,et al.Characteristics of Critically Ill Patients in ICUs in Mainland China[J].CRITICAL CARE MEDICINE.2013,41(1):84-92.doi:10.1097/CCM.0b013e31826a4082.
APA：
Du, Bin,An, Youzhong,Kang, Yan,Yu, Xiangyou,Zhao, Mingyan...&Zhou, Lihua.(2013).Characteristics of Critically Ill Patients in ICUs in Mainland China.CRITICAL CARE MEDICINE,41,(1)
MLA：
Du, Bin,et al."Characteristics of Critically Ill Patients in ICUs in Mainland China".CRITICAL CARE MEDICINE 41..1(2013):84-92
医学