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Epidemiological comparison of clinical manifestations according to HLA-B*27 carrier status of Chinese Ankylosing Spondylitis patients

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WOS体系：
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收录情况： ◇ SCIE

作者：
Yang, M.[1] * ; Xu, M.[1] ; Pan, X.[2] ; Hu, Z.[1] ; Li, Q.[1] ; Wei, Y.[1] ; Zhang, Y.[1] ; Rong, J.[1] ; Zhai, J.[1] ; He, P.[3] ; Hu, S.[3] ; Song, H.[4] ; Wu, H.[4] ; Zhan, F.[5] ; Liu, S.[6] ; Gao, G.[6] ; Liu, Z.[6] ; Li, Y.[7] ; Shen, L.[8] ; Huang, A.[8] ; Lin, Z.[1] ; Liao, Z.[1] ; Cao, S.[1] ; Wei, Q.[1] ; Li, Q.[1] ; Lv, Q.[1] ; Qi, J.[1] ; Li, T.[1] ; Jin, O.[1] ; Pan, Y.[1] ; Gu, J.[1,*1] ;
单位： [1]Sun Yat Sen Univ, Affiliated Hosp 3, Dept Rheumatol & Immunol, Guangzhou 510630, Guangdong, Peoples R China [2]Soochow Univ, Affiliated Hosp 3, Peoples Hosp Changzhou 1, Dept Rheumatol & Immunol, Suzhou, Peoples R China [3]Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Dept Immunol & Rheumatol, Wuhan 430074, Peoples R China [4]Beijing Jishuitan Hosp, Dept Rheumatol & Immunol, Beijing, Peoples R China [5]Hainan Prov Peoples Hosp, Dept Rheumatol, Haikou, Peoples R China [6]Zhengzhou Univ, Affiliated Hosp 1, Dept Urol & Rheumatol, Zhengzhou 450052, Peoples R China [7]Nanjing Mil Command, Dept Rheumatol, Fuzhou Gen Hosp, Fuzhou, Peoples R China [8]Huazhong Univ Sci & Technol, Tongji Med Coll, Union Hosp, Dept Immunol & Rheumatol, Wuhan 430074, Peoples R China
出处：
DOI： 10.1111/tan.12186
ISSN：

关键词： ankylosing spondylitis clinical manifestations HLA-B27

摘要：
The aim of the study was to investigate and compare the clinical manifestations between HLA-B27(+) and HLA-B27(-) ankylosing spondylitis (AS) patients in order to obtain knowledge of the impact of HLA-B27 status on AS, and to inform clinical treatment. A nationwide epidemiological investigation was performed from November 2008 to October 2010. The demographic data and clinical characteristics, and the status of HLA-B27 were collected using questionnaires and laboratory assay, respectively. A total of 2144 patients (78.5% males and 78.4% HLA-B27(+)AS patients) participated in this study. The percentages of males, patients with family history, and involvement of lumbar spine, thoracic spine and hip joints, were observed to be significantly higher in the HLA-B27(+) AS patients than in their HLA-B27(-)AS peers.

基金：
National Natural Sciences Foundation of China [31070806]; Ministry of Public Health of China; Foundation of Guangdong province of China [2005A30801005, 2009B080701086]; State Board of Education Fund for the Doctoral [20060558046]; Guangzhou Science and Technology Plan Projects [2006Z2-E0221]; Sun Yat-sen University
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2012]版：
大类 | 3 区 医学
小类 | 3 区 病理学 4 区 细胞生物学 4 区 免疫学
最新[2025]版：
无
JCR分区：
出版当年[2011]版：
Q2 PATHOLOGY Q3 CELL BIOLOGY Q3 IMMUNOLOGY
最新[2023]版：
无

影响因子： 最新[2023版] 最新五年平均 出版当年[2011版] 出版当年五年平均 出版前一年[2010版] 出版后一年[2012版]

第一作者：
第一作者单位： [1]Sun Yat Sen Univ, Affiliated Hosp 3, Dept Rheumatol & Immunol, Guangzhou 510630, Guangdong, Peoples R China
通讯作者：
通讯机构： [1]Sun Yat Sen Univ, Affiliated Hosp 3, Dept Rheumatol & Immunol, Guangzhou 510630, Guangdong, Peoples R China [*1]Sun Yat Sen Univ, Affiliated Hosp 3, Dept Rheumatol, 600 Tianhe Rd, Guangzhou 510630, Guangdong, Peoples R China
推荐引用方式(GB/T 7714)：
Yang M.,Xu M.,Pan X.,et al.Epidemiological comparison of clinical manifestations according to HLA-B*27 carrier status of Chinese Ankylosing Spondylitis patients[J].TISSUE ANTIGENS.2013,82(5):338-343.doi:10.1111/tan.12186.
APA：
Yang, M.,Xu, M.,Pan, X.,Hu, Z.,Li, Q....&Gu, J..(2013).Epidemiological comparison of clinical manifestations according to HLA-B*27 carrier status of Chinese Ankylosing Spondylitis patients.TISSUE ANTIGENS,82,(5)
MLA：
Yang, M.,et al."Epidemiological comparison of clinical manifestations according to HLA-B*27 carrier status of Chinese Ankylosing Spondylitis patients".TISSUE ANTIGENS 82..5(2013):338-343

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