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Associations of depression with impaired glucose regulation, newly diagnosed diabetes and previously diagnosed diabetes in Chinese adults

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收录情况： ◇ SCIE

作者：
Sun, J. C.[1,2,3] * ; Xu, M.[3] ; Lu, J. L.[3] ; Bi, Y. F.[3,4] ; Mu, Y. M. ; Zhao, J. J.[5] ; Liu, C.[6] ; Chen, L. L.[7] ; Shi, L. X.[8] ; Li, Q.[9] ; Yang, T.[10] ; Yan, L.[11] ; Wan, Q.[12] ; Wu, S. L.[13] ; Liu, Y.[14] ; Wang, G. X.[14] ; Luo, Z. J.[15] ; Tang, X. L.[16] ; Chen, G.[17] ; Huo, Y. N.[18] ; Gao, Z. N.[19] ; Su, Q.[20] ; Ye, Z.[21] ; Wang, Y. M.[22] ; Qin, G. J.[23] ; Deng, H. C.[24] ; Yu, X. F.[25] ; Shen, F. X.[26] ; Chen, L.[27] ; Zhao, L. B.[3] ; Wang, T. G.[3] ; Lai, S. H.[28] ; Li, D. H.[29] ; Wang, W. Q.[3] ; Ning, G.[1,2,3] ;
单位： [1]Chinese Acad Sci, Shanghai Inst Biol Sci, Lab Endocrine & Metab Dis, Inst Hlth Sci, Shanghai, Peoples R China [2]Shanghai Jiao Tong Univ, Sch Med, Shanghai 200030, Peoples R China [3]Shanghai Jiao Tong Univ, Shanghai Clin Ctr Endocrine & Metab Dis, Dept Endocrine & Metab Dis,Sch Med, Shanghai Inst Endocrine & Metab Dis,Rui Jin Hosp, Shanghai 200030, Peoples R China [4]Peoples Liberat Army Gen Hosp, Beijing, Peoples R China [5]Shandong Prov Hosp, Jinan, Peoples R China [6]Jiangsu Prov Hosp Integrat Chinese & Western Med, Nanjing, Jiangsu, Peoples R China [7]Huazhong Univ Sci & Technol, Sch Med, Wuhan Xiehe Hosp, Wuhan 430074, Peoples R China [8]Guiyang Med Coll, Affiliated Hosp, Guiyang, Peoples R China [9]Haerbin Med Univ, Affilliated Hosp 2, Haerbin, Peoples R China [10]Nanjing Med Univ, Jiangsu Prov Hosp, Affiliated Hosp 1, Nanjing, Jiangsu, Peoples R China [11]Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Guangzhou 510275, Guangdong, Peoples R China [12]Luzhou Med Coll, Affiliated Hosp, Luzhou, Peoples R China [13]Xinjiang Kelamayi Peoples Hosp, Kelamayi, Peoples R China [14]Jilin Univ, Hosp 1, Changchun 130023, Peoples R China [15]Guangxi Med Univ, Affiliated Hosp 1, Nanning, Peoples R China [16]Lanzhou Univ, Hosp 1, Lanzhou 730000, Peoples R China [17]Fujian Med Univ, Fujian Prov Hosp, Fuzhou, Peoples R China [18]Jiangxi Peoples Hosp, Nanchang, Peoples R China [19]Dalian Municipal Cent Hosp, Dalian, Peoples R China [20]Shanghai Jiao Tong Univ, Sch Med, Xinhua Hosp, Shanghai 200030, Peoples R China [21]Zhejiang Ctr Dis Control & Prevent, Hangzhou, Zhejiang, Peoples R China [22]Anhui Med Univ, Affiliated Hosp 1, Hefei, Peoples R China [23]Zhengzhou Univ, Affiliated Hosp 1, Zhengzhou 450052, Peoples R China [24]Chongqing Med Univ, Affiliated Hosp 1, Chongqing, Peoples R China [25]Huazhong Univ Sci & Technol, Sch Med, Wuhan Tongji Hosp, Wuhan 430074, Peoples R China [26]Wenzhou Med Univ, Prov Wenzhou Hosp Zhejiang 1, Affiliated Hosp 1, Wenzhou, Peoples R China [27]Shandong Univ, Sch Med, Qilu Hosp, Jinan 250100, Peoples R China [28]Johns Hopkins Univ, Sch Med, Baltimore, MD USA [29]Univ Texas MD Anderson Canc Ctr, Dept Gastrointestinal Med Oncol, Houston, TX 77030 USA
出处：
DOI： 10.1111/dme.12649
ISSN：

摘要：
Aim To examine the association between depression and impaired glucose regulation, newly diagnosed diabetes and previously diagnosed diabetes in middle-aged and elderly Chinese people, and whether depression was associated with different treatment regimens or durations of diabetes. Methods A cross-sectional study was performed among 229 047 adults living in the community aged 40 years from 25 centres in China. The self-reported depression rating scale Patient Health Questionnaire 9 (PHQ-9) was used to diagnose probable and sub-threshold depression. Glucose metabolism status was determined according to World Health Organization 1999 diagnostic criteria. Results The numbers of participants with normal glucose regulation, impaired glucose regulation, newly diagnosed diabetes and previously diagnosed diabetes were 120 458, 59 512, 24 826 and 24 251, respectively. The prevalence of subthreshold depression in the total sample of participants was 4.8% (4.8%, 4.8%, 4.4% and 5.6% from normal glucose regulation to previously diagnosed diabetes, respectively), and the prevalence of probable depression was 1.1% (1.1%, 1.0%, 0.9% and 1.8% from normal glucose regulation to previously diagnosed diabetes, respectively). Compared with participants with normal glucose regulation, those with previously diagnosed diabetes had increased odds of probable depression [odds ratio (OR) = 1.61, 95% confidence interval (CI) 1.39-1.87] and sub-threshold depression (OR = 1.14, 95% CI 1.06-1.24), after adjustment for multiple confounding factors. Newly diagnosed diabetes or impaired glucose regulation was not associated with depression. Among those with previously diagnosed diabetes, insulin treatment was associated with greater odds of depression compared with no treatment or oral anti-diabetic medicine. Conclusion Previously diagnosed diabetes, but not newly diagnosed diabetes or impaired glucose regulation, was associated with a higher prevalence of depression. Patients receiving insulin were more likely to have depression than those not receiving treatment or being treated with oral anti-diabetic medicine.

基金：
Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health [1994DP131044]; National Clinical Research Center for Metabolic Diseases of Ministry of Health [2013BAI09B13]; National Key New Drug Creation and Manufacturing Program of Ministry of Science and Technology [2012ZX09303006-001]; National High Technology Research and Development Program of China [2012AA020A509]; National Natural Science Foundation of China [81321001, 81222008, 81390350, 81370960, 81130016, 81270877]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2014]版：
大类 | 3 区 医学
小类 | 3 区 内分泌学与代谢
最新[2025]版：
大类 | 3 区 医学
小类 | 3 区 内分泌学与代谢
JCR分区：
出版当年[2013]版：
Q2 ENDOCRINOLOGY & METABOLISM
最新[2023]版：
Q2 ENDOCRINOLOGY & METABOLISM

影响因子： 最新[2023版] 最新五年平均 出版当年[2013版] 出版当年五年平均 出版前一年[2012版] 出版后一年[2014版]

第一作者：
第一作者单位： [1]Chinese Acad Sci, Shanghai Inst Biol Sci, Lab Endocrine & Metab Dis, Inst Hlth Sci, Shanghai, Peoples R China [2]Shanghai Jiao Tong Univ, Sch Med, Shanghai 200030, Peoples R China [3]Shanghai Jiao Tong Univ, Shanghai Clin Ctr Endocrine & Metab Dis, Dept Endocrine & Metab Dis,Sch Med, Shanghai Inst Endocrine & Metab Dis,Rui Jin Hosp, Shanghai 200030, Peoples R China
通讯作者：
通讯机构： [1]Chinese Acad Sci, Shanghai Inst Biol Sci, Lab Endocrine & Metab Dis, Inst Hlth Sci, Shanghai, Peoples R China [2]Shanghai Jiao Tong Univ, Sch Med, Shanghai 200030, Peoples R China [3]Shanghai Jiao Tong Univ, Shanghai Clin Ctr Endocrine & Metab Dis, Dept Endocrine & Metab Dis,Sch Med, Shanghai Inst Endocrine & Metab Dis,Rui Jin Hosp, Shanghai 200030, Peoples R China
推荐引用方式(GB/T 7714)：
Sun J. C.,Xu M.,Lu J. L.,et al.Associations of depression with impaired glucose regulation, newly diagnosed diabetes and previously diagnosed diabetes in Chinese adults[J].DIABETIC MEDICINE.2015,32(7):935-943.doi:10.1111/dme.12649.
APA：
Sun, J. C.,Xu, M.,Lu, J. L.,Bi, Y. F.,Mu, Y. M....&Ning, G..(2015).Associations of depression with impaired glucose regulation, newly diagnosed diabetes and previously diagnosed diabetes in Chinese adults.DIABETIC MEDICINE,32,(7)
MLA：
Sun, J. C.,et al."Associations of depression with impaired glucose regulation, newly diagnosed diabetes and previously diagnosed diabetes in Chinese adults".DIABETIC MEDICINE 32..7(2015):935-943

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