AimsFew studies have analysed the effect of sleep duration and snoring on hypertension and glycaemic control in patients with diabetes. This study aims to investigate the relationship of sleep duration and snoring on prevalent hypertension and glycaemic control in people with diabetes. MethodsIn the baseline survey of the REACTION study, 56032 patients with diabetes were categorized into four groups according to self-reported sleep duration: <6, 6-7.9, 8-8.9 and 9h. Snoring frequency was evaluated as usually', occasionally' or never'. Hypertension was assessed by systolic blood pressure, diastolic blood pressure, self-reported previous diagnosis and antihypertensive medications. Good' glycaemic control was defined as HbA(1c) <53mmol/mol (7.0%) and poor' glycaemic control as HbA(1c) 53mmol/mol (7.0%). ResultsControlling for potential confounders and intermediates, sleep 9h relative to intermediate sleep (6-7.9h) was significantly associated with prevalent hypertension (OR: 1.25, 95% CI: 1.18-1.32) and poor glycaemic control (OR: 1.11, 95% CI: 1.05-1.18), and a U-shaped association was found between sleep duration and prevalent hypertension (P for quadratic trend=0.019). Usually snoring was positively associated with prevalent hypertension (OR: 1.30, 95% CI: 1.23-1.37), whereas the association between snoring and poor glycaemic control was only on the borderline of statistical significance. ConclusionsCompared with a sleep duration of 6-7.9h, longer sleep duration was associated with a higher prevalence of hypertension and poor glycaemic control in people with diabetes. Moreover, the relationship between sleep duration and prevalent hypertension was U-shaped. These findings may propose important public health implications for diabetes management. What's new? <list list-type="bulleted" id="dme12809-list-0001"> Longer sleep duration (8h) was positively associated with prevalent hypertension and poor glycaemic control in patients with diabetes, and the association between sleep duration and prevalent hypertension was U-shaped. The findings may have implications for diabetes management.
基金:
Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health [1994DP131044]; National Clinical Research Center for Metabolic Diseases of Ministry of Health [2013BAI09B13]; National Key New Drug Creation and Manufacturing Program of Ministry of Science and Technology [2012ZX09303006-001]; National High Technology Research and Development Program of China (863 Program) [2011AA020107]; National Natural Science Foundation of China [81030011, 81222008, 81130016]; Shanghai Municipal of Science and Technology [13495810200]; 'Yang Fan Project for Young Scientist' of Shanghai Science and Technology Committee [15YF1410100]
第一作者单位:[1]Shanghai Jiao Tong Univ, Sch Med,Minist Hlth, State Key Lab Med Genom,Key Lab Endocrine & Metab, Natl Clin Res Ctr Metab Dis,Collaborat Innovat Ct, Shanghai 200030, Peoples R China[2]Shanghai Jiao Tong Univ, Sch Med, Rui Jin Hosp, Shanghai Clin Ctr Endocrine & Metab Dis, Shanghai 200030, Peoples R China
通讯作者:
通讯机构:[1]Shanghai Jiao Tong Univ, Sch Med,Minist Hlth, State Key Lab Med Genom,Key Lab Endocrine & Metab, Natl Clin Res Ctr Metab Dis,Collaborat Innovat Ct, Shanghai 200030, Peoples R China[2]Shanghai Jiao Tong Univ, Sch Med, Rui Jin Hosp, Shanghai Clin Ctr Endocrine & Metab Dis, Shanghai 200030, Peoples R China
推荐引用方式(GB/T 7714):
Wang T.,Lu J.,Wang W.,et al.Sleep duration and snoring associate with hypertension and glycaemic control in patients with diabetes[J].DIABETIC MEDICINE.2015,32(8):1001-1007.doi:10.1111/dme.12809.
APA:
Wang, T.,Lu, J.,Wang, W.,Mu, Y.,Zhao, J....&Ning, G..(2015).Sleep duration and snoring associate with hypertension and glycaemic control in patients with diabetes.DIABETIC MEDICINE,32,(8)
MLA:
Wang, T.,et al."Sleep duration and snoring associate with hypertension and glycaemic control in patients with diabetes".DIABETIC MEDICINE 32..8(2015):1001-1007