单位：[1]Huazhong Univ Sci & Technol,Inst Integrated Tradit Chinese & Western Med,Tongji Hosp,Tongji Med Collage,Wuhan,Hubei,Peoples R China中西医结合研究所中西医结合科华中科技大学同济医学院附属同济医院
Background: Vasa (a DEAD-box helicase, also known as Ddx4) is an ATP-dependent RNA helicase highly conserved among all animals. Research on the presence and function of DDX4 in female mammals is limited. To gain greater insight into its distribution and role in female mice, we detected the expression of DDX4 protein in the ovaries and analyzed its expression pattern. Material/Methods: MVH was detected in the cytoplasm of oocytes in all non-apoptotic follicles. Results: In the present study, we found that higher expression levels of similar to 55-60 kDa MVH isoform in the ovaries were followed by the accumulations of preovulatory follicles. Conclusions: Higher levels of MVH protein in the ovaries might prepare oocytes for the competence to resume meiosis.
基金：
National Natural Science Foundation of China [81173396]
第一作者单位：[1]Huazhong Univ Sci & Technol,Inst Integrated Tradit Chinese & Western Med,Tongji Hosp,Tongji Med Collage,Wuhan,Hubei,Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Song Kunkun,Ma Wenwen,Huang Cong,et al.Expression Pattern of Mouse Vasa Homologue (MVH) in the Ovaries of C57BL/6 Female Mice[J].MEDICAL SCIENCE MONITOR.2016,22:2656-2663.doi:10.12659/MSM.899830.
APA：
Song, Kunkun,Ma, Wenwen,Huang, Cong,Ding, Jiahui,Cui, Dandan&Zhang, Mingmin.(2016).Expression Pattern of Mouse Vasa Homologue (MVH) in the Ovaries of C57BL/6 Female Mice.MEDICAL SCIENCE MONITOR,22,
MLA：
Song, Kunkun,et al."Expression Pattern of Mouse Vasa Homologue (MVH) in the Ovaries of C57BL/6 Female Mice".MEDICAL SCIENCE MONITOR 22.(2016):2656-2663
