Background: Trigeminal neuralgia (TN) caused by vertebrobasilar dolichoectasia (VBD) is rare and needs further exploration. The purpose of this study is to investigate the clinical features and surgical treatment of TN caused by VBD. Methods: 15 patients with TN caused by VBD were included in our study. The patient data regarding clinical characteristics, neuroimaging presentations, intraoperative findings and treatment outcomes were analyzed retrospectively. Moreover, the previous relevant literature was reviewed simultaneously. Simple MVD was performed in 13 cases and MVD plus trigeminal nerve selective partial posterior rhizotomy (SPPR) was conducted in 2 patients. Results: Of all patients, 7 cases were female and 8 were male. The average age at operationwas 60.8 years old (range, 35yrs-75yrs). 13 patients suffered from hypertension and 7 had a history of stoke. The extended and ectatic vetebrobasilar artery (VBA) was preliminarily identified in preoperative imaging presentations and finally confirmed during surgical procedure. The facial neuralgia disappeared immediately after surgery in all patients. All patients were relieved of pain (BNI score I) with an average of 29.8 months follow-up. Conclusions: Our results suggest that simple MVD is effective for TN caused by VBD. MVD plus SPPR can be cautiously performed if patient has advanced age and is susceptible to numbness. (C) 2017 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.