Aberrant overexpression of long non-coding RNA CRNDE (Colorectal Neoplasia Differentially Expressed) is confirmed in various human cancers, which is correlated with advanced clinicopathological features and poor prognosis. CRNDE promotes cancer cell proliferation, migration and invasion, and suppresses apoptosis in complicated mechanisms, which result in the initialization and development of human cancers. In this review, we provide an overview of the oncogenic role and potential clinical applications of CRNDE.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81502657]
第一作者单位：[1]Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Ctr Canc, Wuhan, Hubei, Peoples R China[2]Huazhong Univ Sci & Technol,Tongji Hosp,Dept Orthoped,Tongji Med Coll,Wuhan,Hubei,Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Zhang Jiaming,Yin Minuo,Peng Gang,et al.CRNDE: An important oncogenic long non-coding RNA in human cancers[J].CELL PROLIFERATION.2018,51(3):doi:10.1111/cpr.12440.
APA：
Zhang, Jiaming,Yin, Minuo,Peng, Gang&Zhao, Yingchao.(2018).CRNDE: An important oncogenic long non-coding RNA in human cancers.CELL PROLIFERATION,51,(3)
MLA：
Zhang, Jiaming,et al."CRNDE: An important oncogenic long non-coding RNA in human cancers".CELL PROLIFERATION 51..3(2018)
生物学