Rationale and Objectives: This study aimed to establish diffusion quantitative parameters (apparent diffusion coefficient [ADC], DDC, alpha, D-app, and K-app) in normal testes at 3.0 T. Materials and methods: Sixty-four healthy volunteers in two age groups (A: 10-39 years; B: 40 years) underwent diffusion weighted imaging scanning at 3.0 T. ADC(1000), ADC(2000), ADC(3000), DDC, a, D-app, and K-app were calculated using the mono-exponential, stretched-exponential, and kurtosis models. The correlations between parameters and the age were analyzed. The parameters were compared between the age groups and between the right and the left testes. Results: The average ADC(1000), ADC(2000), ADC(3000), DDC, alpha, D-app, and K-app, values did not significantly differ between the right and the left testes (P >.05 for all). The following significant correlations were found: positive correlations between age and testicular ADC(1000), ADC(2000), ADC(3000), DDC, and D-app (r = 0.516, 0.518, 0.518, 0.521, and 0.516, respectively; P <.01 for all) and negative correlations between age and testicular a and K-app (r = -0.363, -0.427, respectively; P <.01 for both). Compared to group B, in group A, ADC(1000), ADC(2000), ADC(3000), DDC, and D-app were significantly lower (P <.05 for all), but a and K-app were significantly higher (P <.05 for both). Conclusions: Our study demonstrated the applicability of the testicular mono-exponential, stretched-exponential, and kurtosis models. Our results can help establish a baseline for the normal testicular parameters in these diffusion models. The contralateral normal testis can serve as a suitable reference for evaluating the abnormalities of the other side. The effect of age on these parameters requires further attention.
基金:
National Natural Science Foundation of China [81671656, 81171307]
第一作者单位:[1]Huazhong Univ Sci & Technol, Tongji Hosp, Dept Radiol, Tongji Med Coll, 1095 Jie Fang Ave, Wuhan 430030, Hubei, Peoples R China
通讯作者:
推荐引用方式(GB/T 7714):
Min Xiangde,Feng Zhaoyan,Wang Liang,et al.Multi-model Analysis of Diffusion-weighted Imaging of Normal Testes at 3.0 T: Preliminary Findings[J].ACADEMIC RADIOLOGY.2018,25(4):445-452.doi:10.1016/j.acra.2017.11.004.
APA:
Min, Xiangde,Feng, Zhaoyan,Wang, Liang,Cai, Jie,Li, Basen...&Yan, Xu.(2018).Multi-model Analysis of Diffusion-weighted Imaging of Normal Testes at 3.0 T: Preliminary Findings.ACADEMIC RADIOLOGY,25,(4)
MLA:
Min, Xiangde,et al."Multi-model Analysis of Diffusion-weighted Imaging of Normal Testes at 3.0 T: Preliminary Findings".ACADEMIC RADIOLOGY 25..4(2018):445-452