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Multi-model Analysis of Diffusion-weighted Imaging of Normal Testes at 3.0 T: Preliminary Findings

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单位: [1]Huazhong Univ Sci & Technol, Tongji Hosp, Dept Radiol, Tongji Med Coll, 1095 Jie Fang Ave, Wuhan 430030, Hubei, Peoples R China [2]Yangtze Univ, Dept Radiol, Jingzhou Peoples Hosp 1, Jingzhou 434000, Hubei, Peoples R China [3]Yangtze Univ, Affiliated Hosp 1, Jingzhou 434000, Hubei, Peoples R China [4]Siemens Healthcare, MR Collaborat NE Asia, Shanghai, Peoples R China
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关键词: Testis diffusion-weighted imaging mono-exponential model stretched-exponential model diffusion kurtosis imaging

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Rationale and Objectives: This study aimed to establish diffusion quantitative parameters (apparent diffusion coefficient [ADC], DDC, alpha, D-app, and K-app) in normal testes at 3.0 T. Materials and methods: Sixty-four healthy volunteers in two age groups (A: 10-39 years; B: 40 years) underwent diffusion weighted imaging scanning at 3.0 T. ADC(1000), ADC(2000), ADC(3000), DDC, a, D-app, and K-app were calculated using the mono-exponential, stretched-exponential, and kurtosis models. The correlations between parameters and the age were analyzed. The parameters were compared between the age groups and between the right and the left testes. Results: The average ADC(1000), ADC(2000), ADC(3000), DDC, alpha, D-app, and K-app, values did not significantly differ between the right and the left testes (P >.05 for all). The following significant correlations were found: positive correlations between age and testicular ADC(1000), ADC(2000), ADC(3000), DDC, and D-app (r = 0.516, 0.518, 0.518, 0.521, and 0.516, respectively; P <.01 for all) and negative correlations between age and testicular a and K-app (r = -0.363, -0.427, respectively; P <.01 for both). Compared to group B, in group A, ADC(1000), ADC(2000), ADC(3000), DDC, and D-app were significantly lower (P <.05 for all), but a and K-app were significantly higher (P <.05 for both). Conclusions: Our study demonstrated the applicability of the testicular mono-exponential, stretched-exponential, and kurtosis models. Our results can help establish a baseline for the normal testicular parameters in these diffusion models. The contralateral normal testis can serve as a suitable reference for evaluating the abnormalities of the other side. The effect of age on these parameters requires further attention.

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出版当年[2017]版:
大类 | 4 区 医学
小类 | 3 区 核医学
最新[2025]版:
大类 | 2 区 医学
小类 | 2 区 核医学
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出版当年[2016]版:
Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
最新[2023]版:
Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

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第一作者单位: [1]Huazhong Univ Sci & Technol, Tongji Hosp, Dept Radiol, Tongji Med Coll, 1095 Jie Fang Ave, Wuhan 430030, Hubei, Peoples R China
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