A novel bright near-infrared II (NIR-II, 1000-1700 nm) fluorescent probe with excellent water-solubility, superior photostability, and excellent in vitro and in vivo biocompatibility was facilely synthesized for in vivo biomedical imaging of xenograft breast tumor and chemically induced spontaneous breast carcinoma. To the best of our knowledge, it is the first time that the superior practical applications of this NIR-II probe in dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma imaging and image-guided rat carcinoma surgery were demonstrated.
基金：
NSFC [81773674, 81573383, 21473041]; NSFHP [2017CFB641, 2017CFA024, 2017CFB711, 2016ACA126]; Applied Basic Research Program of WMBST [2019020701011429, 2019020701011436]; Fundamental Research Funds for the Central Universities; Tibet Autonomous Region Science and Technology Plan Project Key Project [XZ201901-GB-11]; Chengdu University of Traditional Chinese Medicine [CZYJC1903]; Health Commission of Hubei Province Scientific Research Project [WJ2019M177, WJ2019M178]
化学