Objective: The aim of the current study was to methodically analyze the application value of shear-wave elastosonography (SWE) for diagnosis of prostatic cancer (PCa) via meta-analysis. Methods: Relevant studies concerning diagnosis of PCa using SWE, published before October 31, 2018, in China and other countries, were collected. These studies were filtered and estimated in terms of diagnostic criteria. Selected references were handled using Meta-disc 1.4, Revman 5.3, and Stata 14.0. Results: A total of 16 studies were finally included. After meta-analysis, the following values were drawn: PSNE = 0.84 [95% CI (0.76, 0.89)], PSPE = 0.85 [95% CI (0.78, 0.90)], PLR = 5.7 [95% CI (3.6, 8.9)], NLR = 0.19 [95% CI (0.12, 0.30)], DOR = 27.69 [95% CI (11.71, 65.48)], and AUC = 0.91 [95% CI (0.88, 0.93)]. Next, meta regression was analyzed, exploring heterogeneity. The number of ROIs in per-core and levels of research were significant factors affecting heterogeneity (p < 0.01 and p = 0.04, respectively). Conclusion: SWE exhibited a favorable diagnostic value for detection of PCa. However, no clear inference could be made concerning cut-off values due to inescapable heterogeneity. In future investigations, specific recommendations regarding experimental design, especially included and excluded covariates, should be considered.