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Aquaporin-4 antibody positive neuromyelitis optica spectrum disorder subsequent to rhabdomyolysis: a case report and literature review

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收录情况： ◇ SCIE

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单位： [1]Huazhong Univ Sci & Technol,Tongji Med Coll,Tongji Hosp,Dept Neurol,Wuhan 430030,Hubei,Peoples R China

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关键词： NMOSD AQP4 Rhabdomyolysis hyperCKemia

摘要：

Rhabdomyolysis could be caused by various mechanisms including autoimmune reaction. Here, we reported a case of 76-year-old-woman diagnosed with aquaporin-4 (AQP4) IgG positive neuromyelitis optica spectrum disorder (NMOSD) following rhabdomyolysis. After a review of literature, we propose that physical injury of skeletal muscle cells may lead to the production of AQP4 IgG and this AQP4 IgG might further decrease in the stability of skeletal muscle cells creating a positive feedback loop. HyperCKemia might be an inducement of NMOSD.

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出版当年[2018]版：

大类 | 4 区医学

小类 | 4 区神经科学

最新[2025]版：

大类 | 4 区医学

小类 | 4 区神经科学

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出版当年[2017]版：

Q4 NEUROSCIENCES

最新[2023]版：

Q4 NEUROSCIENCES

影响因子： 1.7 最新[2023版] 2 最新五年平均 1.848 出版当年[2017版] 1.71 出版当年五年平均 1.75 出版前一年[2016版] 1.852 出版后一年[2018版]

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第一作者单位： [1]Huazhong Univ Sci & Technol,Tongji Med Coll,Tongji Hosp,Dept Neurol,Wuhan 430030,Hubei,Peoples R China

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