Background: Obesity and arterial stiffness are both independently associated with cardiovascular risk. New anthropometric indices can better reflect abdominal obesity than traditional anthropometric indices. Thus, we hypothesized that compared with conventional parameters, these newly developed anthropometric parameters were more accurate to identify arterial stiffness among overweight and obesity population. Methods: Cross-sectional data on socio-demographic, lifestyle, clinical characteristics and biochemical measurements were collected for 1442 Chinese obese and overweight adults. Six anthropometric indices including a body shape index (ABSI), body mass index (BMI), ABSI combined with BM], body roundness index (BRI), waist circumference and waist-to-hip ratio were calculated. Carotid-femoral pulse wave velocity (cf-PWV) was detected in all subjects. Meanwhile, visceral fat area (VFA) was quantificationally measured by CT. Partial Spearman correlation coefficients were used to clarify the association between anthropometric measures with cf-PWV. Logistic regression analyses were used to identify to the association between anthropometric measures and arterial stiffness. Results: After adjusting for covariates, BRI had the strongest correlation with cf-PWV and VFA in all anthropometric indices. Multivariate regression analysis showed VFA (beta = 0.322, p < 0.001) and BRI (beta = 0.307, p < 0.001) remained independently associated with cf-PWV. BRI had a highest odds ratios in all anthropometric indices (OR = 1.543, p < 0.001). ABSI only displayed a weak correlation with arterial stiffness. Meanwhile, BRI had the highest area under curve for abnormal cf-PWV, and the optimum cutoff value was a BRI >= 5.4. Conclusion: BRI was found to have a close relationship with arterial stiffness in overweight and obesity people. However, ABSI was weakly correlated with arterial stiffness, but not better than traditional anthropometric indices. (C) 2019 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
基金:
Hospital Talents Support Fund of Hubei Provincial Hospital of TCM [201612022B]; Natural Science Foundation of Hubei Province of China [2018CFB699]
第一作者单位:[1]Hubei Prov Hosp Tradit Chinese Med, Emergency Dept, Wuhan 430061, Peoples R China[2]Hubei Prov Acad Tradit Chinese Med, Wuhan, Peoples R China
通讯作者:
推荐引用方式(GB/T 7714):
Li Gang,Yao Tao,Wu Xiao-wei,et al.Novel and traditional anthropometric indices for identifying arterial stiffness in overweight and obese adults[J].CLINICAL NUTRITION.2020,39(3):893-900.doi:10.1016/j.clnu.2019.03.029.
APA:
Li, Gang,Yao, Tao,Wu, Xiao-wei,Cao, Zhe,Tu, Yuan-Chao...&Hou, Jian.(2020).Novel and traditional anthropometric indices for identifying arterial stiffness in overweight and obese adults.CLINICAL NUTRITION,39,(3)
MLA:
Li, Gang,et al."Novel and traditional anthropometric indices for identifying arterial stiffness in overweight and obese adults".CLINICAL NUTRITION 39..3(2020):893-900