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CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research

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收录情况： ◇ SCIE ◇ SSCI ◇ 自然指数

作者：
Xu, Qiang[1,2] * ; Guo, Lining[1,2] ; Cheng, Jingliang[3] ; Wang, Meiyun[4,5,6] ; Geng, Zuojun[7] ; Zhu, Wenzhen[8] ; Zhang, Bing[9] ; Liao, Weihua[10,11] ; Qiu, Shijun[12] ; Zhang, Hui[13] ; Xu, Xiaojun[14] ; Yu, Yongqiang[15] ; Gao, Bo[16] ; Han, Tong[17,18] ; Yao, Zhenwei[19] ; Cui, Guangbin[20,21] ; Liu, Feng[1,2] ; Qin, Wen[1,2] ; Zhang, Quan[1,2] ; Li, Mulin Jun[22] ; Liang, Meng[23] ; Chen, Feng[24] ; Xian, Junfang[25] ; Li, Jiance[26] ; Zhang, Jing[27] ; Zuo, Xi-Nian[28,29] ; Wang, Dawei[30] ; Shen, Wen[31] ; Miao, Yanwei[32] ; Yuan, Fei[33] ; Lui, Su[34,35,36] ; Zhang, Xiaochu[37,38] ; Xu, Kai[39,40] ; Zhang, Long Jiang[41] ; Ye, Zhaoxiang[42] ; Yu, Chunshui[1,2,43] ;
单位： [1]Tianjin Med Univ Gen Hosp, Dept Radiol, Tianjin 300052, Peoples R China [2]Tianjin Med Univ Gen Hosp, Tianjin Key Lab Funct Imaging, Tianjin 300052, Peoples R China [3]Zhengzhou Univ, Affiliated Hosp 1, Dept Magnet Resonance Imaging, Zhengzhou 450052, Peoples R China [4]Zhengzhou Univ Peoples Hosp, Dept Radiol, Zhengzhou 450003, Peoples R China [5]Henan Prov Peoples Hosp, Zhengzhou 450003, Peoples R China [6]Henan Key Lab Med Imaging Neurol Dis, Zhengzhou 450003, Peoples R China [7]Hebei Med Univ, Hosp 2, Dept Med Imaging, Shijiazhuang 050000, Hebei, Peoples R China [8]Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Radiol, Wuhan 430030, Peoples R China [9]Nanjing Univ, Dept Radiol, Med Sch, Drum Tower Hosp, Nanjing 210008, Peoples R China [10]Cent South Univ, Xiangya Hosp, Dept Radiol, Changsha 410008, Peoples R China [11]Natl Clin Res Ctr Geriatr Disorder, Changsha 410008, Peoples R China [12]Guangzhou Univ Chinese Med, Dept Med Imaging, Affiliated Hosp 1, Guangzhou 510405, Peoples R China [13]Shanxi Med Univ, Hosp 1, Dept Radiol, Taiyuan 030001, Peoples R China [14]Zhejiang Univ, Sch Med, Dept Radiol, Affiliated Hosp 2, Hangzhou 310009, Peoples R China [15]Anhui Med Univ, Dept Radiol, Affiliated Hosp 1, Hefei 230022, Peoples R China [16]Yantai Yuhuangding Hosp, Dept Radiol, Yantai 264000, Peoples R China [17]Tianjin Huanhu Hosp, Dept Radiol, Tianjin 300350, Peoples R China [18]Tianjin Key Lab Cerebral Vasc & Neurodegenerat Di, Tianjin 300350, Peoples R China [19]Fudan Univ, Dept Radiol, Huashan Hosp, Shanghai 200040, Peoples R China [20]Mil Med Univ PLA Airforce, Mil Med Univ 4, Funct & Mol Imaging Key Lab Shaanxi Prov, Tangdu Hosp, Xian 710038, Peoples R China [21]Mil Med Univ PLA Airforce, Mil Med Univ 4, Dept Radiol, Tangdu Hosp, Xian 710038, Peoples R China [22]Tianjin Med Univ, Collaborat Innovat Ctr Tianjin Med Epigenet, Sch Basic Med Sci, Tianjin Key Lab Med Epigenet, Tianjin 300070, Peoples R China [23]Tianjin Med Univ, Sch Med Imaging, Tianjin 300203, Peoples R China [24]Hainan Gen Hosp, Dept Radiol, Haikou 570311, Hainan, Peoples R China [25]Capital Med Univ, Beijing Tongren Hosp, Dept Radiol, Beijing 100730, Peoples R China [26]Wenzhou Med Univ, Dept Radiol, Affiliated Hosp 1, Wenzhou 325000, Peoples R China [27]Lanzhou Univ, Dept Magnet Resonance, Hosp 2, Lanzhou 730050, Peoples R China [28]Univ Chinese Acad Sci CAS, Dept Psychol, Beijing 100049, Peoples R China [29]Inst Psychol, CAS Key Lab Behav Sci, Beijing 100101, Peoples R China [30]Shandong Univ, Dept Radiol, Qilu Hosp, Jinan 250012, Peoples R China [31]Tianjin First Ctr Hosp, Dept Radiol, Tianjin 300192, Peoples R China [32]Dalian Med Univ, Dept Radiol, Affiliated Hosp 1, Dalian 116011, Peoples R China [33]Logist Univ Chinese Peoples Armed Police Forces, Pingjin Hosp, Dept Radiol, Tianjin 300162, Peoples R China [34]Sichuan Univ, Ctr Med Imaging, Dept Radiol, West China Hosp, Chengdu 610041, Peoples R China [35]Wenzhou Med Univ, Dept Radiol, Affiliated Hosp 2, Wenzhou 325000, Peoples R China [36]Wenzhou Med Univ, Yuying Childrens Hosp, Wenzhou 325000, Peoples R China [37]Univ Sci & Technol China, CAS Key Lab Brain Funct & Dis, Hefei 230026, Peoples R China [38]Univ Sci & Technol China, Sch Life Sci, Hefei 230026, Peoples R China [39]Xuzhou Med Univ, Affiliated Hosp, Dept Radiol, Xuzhou 221006, Jiangsu, Peoples R China [40]Xuzhou Med Univ, Sch Med Imaging, Xuzhou 221004, Jiangsu, Peoples R China [41]Nanjing Univ, Dept Med Imaging, Jinling Hosp, Med Sch, Nanjing 210002, Peoples R China [42]Tianjin Med Univ Canc Inst & Hosp, Dept Radiol, Natl Clin Res Ctr Canc, Tianjins Clin Res Ctr Canc,Key Lab Canc Prevent &, Tianjin 300060, Peoples R China [43]Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Shanghai 200031, Peoples R China
出处：
DOI： 10.1038/s41380-019-0627-6
ISSN：

摘要：
The Chinese Imaging Genetics (CHIMGEN) study establishes the largest Chinese neuroimaging genetics cohort and aims to identify genetic and environmental factors and their interactions that are associated with neuroimaging and behavioral phenotypes. This study prospectively collected genomic, neuroimaging, environmental, and behavioral data from more than 7000 healthy Chinese Han participants aged 18-30 years. As a pioneer of large-sample neuroimaging genetics cohorts of non-Caucasian populations, this cohort can provide new insights into ethnic differences in genetic-neuroimaging associations by being compared with Caucasian cohorts. In addition to micro-environmental measurements, this study also collects hundreds of quantitative macro-environmental measurements from remote sensing and national survey databases based on the locations of each participant from birth to present, which will facilitate discoveries of new environmental factors associated with neuroimaging phenotypes. With lifespan environmental measurements, this study can also provide insights on the macro-environmental exposures that affect the human brain as well as their timing and mechanisms of action.

语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2019]版：
大类 | 1 区 医学
小类 | 1 区 生化与分子生物学 1 区 神经科学 1 区 精神病学
最新[2025]版：
大类 | 1 区 医学
小类 | 1 区 生化与分子生物学 1 区 神经科学 1 区 精神病学
JCR分区：
出版当年[2018]版：
Q1 NEUROSCIENCES Q1 PSYCHIATRY Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY
最新[2023]版：
Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Q1 NEUROSCIENCES Q1 PSYCHIATRY

影响因子： 最新[2023版] 最新五年平均 出版当年[2018版] 出版当年五年平均 出版前一年[2017版] 出版后一年[2019版]

第一作者：
第一作者单位： [1]Tianjin Med Univ Gen Hosp, Dept Radiol, Tianjin 300052, Peoples R China [2]Tianjin Med Univ Gen Hosp, Tianjin Key Lab Funct Imaging, Tianjin 300052, Peoples R China
通讯作者：
通讯机构： [1]Tianjin Med Univ Gen Hosp, Dept Radiol, Tianjin 300052, Peoples R China [2]Tianjin Med Univ Gen Hosp, Tianjin Key Lab Funct Imaging, Tianjin 300052, Peoples R China [43]Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Shanghai 200031, Peoples R China
推荐引用方式(GB/T 7714)：
Xu Qiang,Guo Lining,Cheng Jingliang,et al.CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research[J].MOLECULAR PSYCHIATRY.2020,25(3):517-529.doi:10.1038/s41380-019-0627-6.
APA：
Xu, Qiang,Guo, Lining,Cheng, Jingliang,Wang, Meiyun,Geng, Zuojun...&Yu, Chunshui.(2020).CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research.MOLECULAR PSYCHIATRY,25,(3)
MLA：
Xu, Qiang,et al."CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research".MOLECULAR PSYCHIATRY 25..3(2020):517-529

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