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APASL clinical practice guidelines on the management of acute kidney injury in acute-on-chronic liver failure

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收录情况： ◇ SCIE

作者：
Maiwall Rakhi[1] * ; Singh Satender Pal[1] ; Angeli Paolo[2] ; Moreau Richard[3,4,5] ; Krag Aleksander[6,7] ; Singh Virender[8] ; Singal Ashwani K[9] ; Tan S S[10] ; Puri Puneet[11] ; Mahtab Mamun[12] ; Lau George[13,14] ; Ning Qin[15,16,17] ; Sharma Manoj Kumar[1] ; Rao P N[18] ; Kapoor Dharmesh[19] ; Gupta Subhash[20] ; Duseja Ajay[21] ; Wadhawan Manav[22] ; Jothimani Dinesh[23] ; Saigal Sanjiv[24] ; Taneja Sunil[21] ; Shukla Akash[25] ; Puri Pankaj[26] ; Govil Deepak[27] ; Pandey Gaurav[28] ; Madan Kaushal[24] ; Eapen C E[29] ; Benjamin Jaya[30] ; Chowdhury Ashok[1] ; Singh Shweta[31] ; Salao Vaishali[32] ; Yang Jin Mo[33] ; Hamid Saeed[34] ; Shalimar[35] ; Jasuja Sanjiv[36] ; Kulkarni Anand V[37] ; Niriella Madund A[38] ; Tevethia Harsh Vardhan[1] ; Arora Vinod[1] ; Mathur R P[39] ; Roy Akash[40] ; Jindal Ankur[1] ; Saraf Neeraj[41] ; Verma Nipun[21] ; De Arka[21] ; Choudhary Narendra S[42] ; Mehtani Rohit[25] ; Chand Phool[1] ; Rudra Omkar[1] ; Sarin Shiv Kumar[1] ;
单位： [1]Department of Hepatology, Institute of Liver and Biliary Sciences, D1 Vasant Kunj, New Delhi 110070, India [2]Department of Internal Medicine and Hepatology, University of Padova, Padua, Italy [3]European Foundation for the Study of Chronic Liver Failure (EF CLIF), European Association for the Study of the Liver (EASL)-CLIF Consortium, and Grifols Chair, Barcelona, Spain [4]Centre de Recherche sur l’Inflammation (CRI), Institut National de la Sante et de la Recherche Medicale (INSERM), Universite Paris-Cite, Paris, France [5]Service d’Hepatologie, Assistance Publique–Hopitaux de Paris (AP-HP), Hopital Beaujon, Clichy, France [6]Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark [7]Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark [8]Punjab Institute of Liver and Biliary Sciences, Mohali, Punjab, India [9]Department of Medicine, University of Louisville School of Medicine, Trager Transplant Center and Jewish Hospital, Louisville, USA [10]Department of Medicine, Hospital Selayang, Bata Caves, Selangor, Malaysia [11]Department of Medicine, Virginia Commonwealth University, Richmond, VA, USA [12]Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh [13]Humanity and Health Medical Group, Humanity and Health Clinical Trial Center, Hong Kong SAR, China [14]The Fifth Medical Center of Chinese, PLA General Hospital, Beijing 100039, China [15]Department and Institute of Infectious Disease,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,China [16]State Key Laboratory for Zoonotic Diseases, Wuhan, China [17]Department of Pediatrics,Tongji Medical College,Tongji Hospital,Huazhong University of Science and Technology,Wuhan,China [18]Department of Hepatology and Nutrition, Asian Institute of Gastroenterology, Hyderabad, India [19]Department of Hepatology, Gleneagles Global Hospitals, Hyderabad, Telangana, India [20]Department of Surgery, Center for Liver and Biliary Sciences, Max Healthcare, Saket, New Delhi, India [21]Department of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India [22]Institute of Digestive & Liver Diseases, BLK Superspeciality Hospital Delhi, New Delhi, India [23]Institute of Liver Disease and Transplantation, Dr Rela Institute and Medical Centre, Bharat Institute of Higher Education and Research, Chennai, India [24]Department of Gastroenterology and Hepatology, Centre for Liver and Biliary Sciences, Max Super Speciality Hospital, Saket, New Delhi, India [25]Department of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, India [26]Fortis Escorts Liver & Digestive Diseases Institute, New Delhi, India [27]Department of Critical Care and Anaesthesia, Medanta-The Medicity, Gurugram, Haryana, India [28]Gastroenterology and Hepatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India [29]Department of Hepatology, Christian Medical College, Vellore, Tamil Nadu, India [30]Department of Clinical Nutrition, Institute of Liver and Biliary Sciences, New Delhi, India [31]Centre for Liver and Biliary Sciences, Max Super Speciality Hospital, Saket, New Delhi, India [32]Department of Critical Care, Fortis Hospital, Mulund, Mumbai, India [33]Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea [34]Department of Hepatology, Aga Khan University, Karachi, Pakistan [35]Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India [36]Department of Nephrology, Indraprastha Apollo Hospitals, New Delhi, India [37]Deparment of Hepatology, AIG Hospitals, Hyderabad, India [38]Department of Medicine, Faculty of Medicine, University of Kelaniya, Colombo, Sri Lanka [39]Department of Nephrology, Institute of Liver and Biliary Sciences, New Delhi, India [40]Department of Gastroenterology, Institute of Gastrosciences and Liver Transplantation, Apollo Hospitals, Kolkata, India [41]Institute of Liver Transplantation and Regenerative Medicine, Medanta-The Medicity, Gurgaon, Delhi (NCR), India [42]Department of Hepatology and Liver Transplantation, Medanta-The Medicity Hospital, Gurugram, Haryana, India
出处：
DOI： 10.1007/s12072-024-10650-0
ISSN：

关键词： AKI ACLF Portal hypertension

摘要：
Acute-on-chronic liver failure (ACLF) is a syndrome that is characterized by the rapid development of organ failures predisposing these patients to a high risk of short-term early death. The main causes of organ failure in these patients are bacterial infections and systemic inflammation, both of which can be severe. For the majority of these patients, a prompt liver transplant is still the only effective course of treatment. Kidneys are one of the most frequent extrahepatic organs that are affected in patients with ACLF, since acute kidney injury (AKI) is reported in 22.8-34% of patients with ACLF. Approach and management of kidney injury could improve overall outcomes in these patients. Importantly, patients with ACLF more frequently have stage 3 AKI with a low rate of response to the current treatment modalities. The objective of the present position paper is to critically review and analyze the published data on AKI in ACLF, evolve a consensus, and provide recommendations for early diagnosis, pathophysiology, prevention, and management of AKI in patients with ACLF. In the absence of direct evidence, we propose expert opinions for guidance in managing AKI in this very challenging group of patients and focus on areas of future research. This consensus will be of major importance to all hepatologists, liver transplant surgeons, and intensivists across the globe.© 2024. Asian Pacific Association for the Study of the Liver.

语种：
外文
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中科院(CAS)分区：
出版当年[2023]版：
大类 | 2 区 医学
小类 | 3 区 胃肠肝病学
最新[2025]版：
大类 | 1 区 医学
小类 | 2 区 胃肠肝病学
JCR分区：
出版当年[2022]版：
Q1 GASTROENTEROLOGY & HEPATOLOGY
最新[2023]版：
Q1 GASTROENTEROLOGY & HEPATOLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2022版] 出版当年五年平均 出版前一年[2021版] 出版后一年[2023版]

第一作者：
第一作者单位： [1]Department of Hepatology, Institute of Liver and Biliary Sciences, D1 Vasant Kunj, New Delhi 110070, India
通讯作者：
推荐引用方式(GB/T 7714)：
Maiwall Rakhi,Singh Satender Pal,Angeli Paolo,et al.APASL clinical practice guidelines on the management of acute kidney injury in acute-on-chronic liver failure[J].Hepatology International.2024,doi:10.1007/s12072-024-10650-0.
APA：
Maiwall Rakhi,Singh Satender Pal,Angeli Paolo,Moreau Richard,Krag Aleksander...&Sarin Shiv Kumar.(2024).APASL clinical practice guidelines on the management of acute kidney injury in acute-on-chronic liver failure.Hepatology International,,
MLA：
Maiwall Rakhi,et al."APASL clinical practice guidelines on the management of acute kidney injury in acute-on-chronic liver failure".Hepatology International .(2024)

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