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Cancer burden attributable to risk factors, 1990-2019: A comparative risk assessment

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单位： [1]Cancer Center,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China. [2]Department of GI Surgery,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,P.R. China. [3]GI Cancer Research Institute,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,P.R. China. [4]Department of Orthopedics,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China. [5]Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. [6]Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan 430030, China. [7]Hubei Clinical Center and Key Laboratory of Intestinal and Colorectal Diseases, Wuhan 430030, China. [8]Department of Medical Record, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan 030032 Shanxi, China.

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An up-to-date comprehensive assessment of the cancer burden attributable to risk factors is essential for cancer prevention. We analyzed the population attributable fraction (PAF) of cancer disability-adjusted life years (DALYs) attributable to 11 level 2 risk factors using data from the Global Burden and Disease Study (GBD) 2019. We highlighted that almost half of the cancer DALYs can be preventable by modifying relevant risk factors. The attributable cancer DALYs increased by 60.42%-105.0 million from 1990 to 2019. Tobacco, dietary risks, alcohol use, high body-mass index, and air pollution were the top five risk factors. The PAFs attributable to high fasting plasma glucose, high body-mass index, and low physical activity have increased worldwide from 1990 to 2019. Unsafe sex was the leading risk factor for women before age of 54. Tailored prevention programs targeted at specific populations should be scaled up to reduce the cancer burden in the future.© 2024 The Author(s).

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出版当年[2023]版：

大类 | 2 区综合性期刊

小类 | 2 区综合性期刊

最新[2025]版：

大类 | 2 区综合性期刊

小类 | 2 区综合性期刊

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出版当年[2022]版：

Q1 MULTIDISCIPLINARY SCIENCES

最新[2023]版：

Q1 MULTIDISCIPLINARY SCIENCES

影响因子： 4.6 最新[2023版] 5 最新五年平均 5.8 出版当年[2022版] 5.8 出版当年五年平均 6.107 出版前一年[2021版] 4.6 出版后一年[2023版]

第一作者：

第一作者单位： [1]Cancer Center,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China.

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通讯作者：

通讯机构： [6]Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan 430030, China. [7]Hubei Clinical Center and Key Laboratory of Intestinal and Colorectal Diseases, Wuhan 430030, China.

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