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Chest CT Radiomics is Feasible in Evaluating Muscle Change in Diabetes Patients

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单位: [1]Department of Radiology, The Central Hospital of Wuhan, Tongji Medical College affiliated to Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China. [2]Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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关键词: Muscle CT Radiomics Diabetes Regression Skeletal muscle

摘要:
Non-invasive imaging methods are still lacking for the evaluation of muscle changes in diabetes.To investigate the feasibility of muscle CT radiomics in evaluating muscle changes in diabetes.60 diabetics and 60 health controls (HC) were assessed with the method of muscle CT radiomics. 93 CT images of radiomics features of the pectoralis major muscle (PMM) were obtained by using the software 3D Slicer and were then compared between diabetics and HC cases. The least absolute shrinkage and selection operator (LASSO) regression method was used to establish a prediction model. The receiver operating characteristic (ROC) curve was used to determine the performance of the model.Diabetics and HC cases differed in 19 radiomics features (P<0.05). By using the LASSO method, 6 features were finally selected. The AUC of the model in the discrimination of diabetics and HC were 0.92 and 0.90, respectively, for the training cohort and validation cohort.Muscle CT radiomics is feasible in evaluating muscle changes in diabetes.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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出版当年[2023]版:
大类 | 4 区 医学
小类 | 4 区 核医学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 核医学
第一作者:
第一作者单位: [1]Department of Radiology, The Central Hospital of Wuhan, Tongji Medical College affiliated to Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China.
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