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Uncovering the Potential Mechanisms and Effects of Hyperuricemia and its Associated Diseases on Male Reproduction

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单位: [1]Department of Nephrology, The First Afliated Hospital of Zhengzhou University, Zhengzhou, China [2]Institute of Integrated Traditional Chinese and Western Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,China [3]The Reproduction Center, Henan Provincial Hospital of Traditional Chinese Medicine, Zhengzhou, China [4]The Reproduction Center, The Third Afliated Hospital of Zhengzhou University, Zhengzhou, China
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关键词: Hyperuricemia Erectile dysfunction Semen Sex hormones Gout Metabolic syndrome

摘要:
Male fertility and metabolic disorders, including obesity and diabetes, are closely connected. Since hyperuricemia and metabolic syndrome are strongly related, male fertility and hyperuricemia may, to some degree, be associated. According to recent studies, hyperuricemia imposes various effects on sex hormones, semen quality, and male erectile dysfunction. Some researchers claim that uric acid worsens male semen and raises the risk of erectile dysfunction (ED), while others state that it safeguards both penile erection and male semen. Additionally, it has been shown that gout and metabolic syndrome also raise the risk of ED. To clarify this controversy, the influence and potential mechanisms of hyperuricemia on ED, semen quality, sex hormone levels, and the effects of hyperuricemia-related disorders on ED will be comprehensively summarized.© 2024. The Author(s), under exclusive licence to Society for Reproductive Investigation.

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出版当年[2023]版:
大类 | 3 区 医学
小类 | 4 区 妇产科学 4 区 生殖生物学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 妇产科学 4 区 生殖生物学
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出版当年[2022]版:
Q2 OBSTETRICS & GYNECOLOGY Q3 REPRODUCTIVE BIOLOGY
最新[2023]版:
Q2 OBSTETRICS & GYNECOLOGY Q2 REPRODUCTIVE BIOLOGY

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第一作者单位: [1]Department of Nephrology, The First Afliated Hospital of Zhengzhou University, Zhengzhou, China
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