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The Changes in the Quantity of Lymphocyte Subpopulations during the Process of Sepsis

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收录情况： ◇ SCIE

作者：

单位： [1]Department of Emergency Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China. [2]Department of Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China. [3]Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China.

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关键词： sepsis lymphocyte depletion revive absolute lymphocyte count innate lymphocyte subgroups effector T lymphocytes B lymphocytes dendritic cells

摘要：

Sepsis remains a global challenge, especially in low- and middle-income countries, where there is an urgent need for easily accessible and cost-effective biomarkers to predict the occurrence and prognosis of sepsis. Lymphocyte counts are easy to measure clinically, and a large body of animal and clinical research has shown that lymphocyte counts are closely related to the incidence and prognosis of sepsis. This review extensively collected experimental articles related to lymphocyte counts since the unification of the definition of sepsis. The article categorizes and discusses the relationship between absolute lymphocyte counts, intrinsic lymphocyte subsets, effector T-lymphocytes, B-lymphocytes, dendritic cells, and the incidence and prognosis of sepsis. The results indicate that comparisons of absolute lymphocyte counts alone are meaningless. However, in addition to absolute lymphocyte counts, innate lymphocyte subsets, effector T-cells, B-lymphocytes, and dendritic cells have shown certain research value in related studies.

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中科院(CAS)分区：

出版当年[2023]版：

大类 | 2 区生物学

小类 | 3 区生化与分子生物学 3 区化学：综合

最新[2025]版：

大类 | 3 区生物学

小类 | 3 区生化与分子生物学 3 区化学：综合

JCR分区：

出版当年[2022]版：

Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Q2 CHEMISTRY, MULTIDISCIPLINARY

最新[2023]版：

Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Q2 CHEMISTRY, MULTIDISCIPLINARY

影响因子： 4.9 最新[2023版] 5.6 最新五年平均 5.6 出版当年[2022版] 6.2 出版当年五年平均 6.208 出版前一年[2021版] 4.9 出版后一年[2023版]

第一作者：

第一作者单位： [1]Department of Emergency Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China. [2]Department of Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China.

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通讯作者：

通讯机构： [1]Department of Emergency Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China. [2]Department of Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China.

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