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Progress in the treatment of chronic intracranial large artery occlusion: Time for large, randomized trials?

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单位: [1]Department of Neurology, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430077, China [2]Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 China [3]The Vivian L. Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, the United States of America [4]Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA, the United States of America [5]Department of Anesthesiology, School of Medicine, Loma Linda University, Loma Linda, CA, the United States of America [6]Department of Neurosurgery, School of Medicine, Loma Linda University, Loma Linda, CA, the United States of America
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关键词: Chronic cerebral artery occlusion Interventional therapy Drug treatment Restenosis

摘要:
Chronic cerebral artery occlusion is an important cause of ischemic stroke, resulting in up to 45% of all ischemic strokes. Therefore, treatment of chronic cerebral artery occlusion is critical to improve outcomes in effected patients. In the past, treatment of chronic cerebral artery occlusion focused on drugs and surgical bypass, but effectiveness and potential benefits are not well-supported. In recent years, endovascular recanalization therapy has become more prominent as a treatment for chronic cerebral artery occlusion, due to advances in endovascular procedures, experience and equipment, as well as more advanced imaging methods. Small clinical studies have shown that interventional therapy for chronic cerebral artery occlusions may be safe and effective, yet, there is still a lack of uniform guidelines. This review discusses the current support for recanalization of chronic intracranial large vessel occlusion.(c) 2022 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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大类 | 4 区 医学
小类 | 4 区 临床神经病学
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Q4 CLINICAL NEUROLOGY

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第一作者单位: [1]Department of Neurology, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430077, China
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通讯机构: [2]Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 China [4]Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA, the United States of America [5]Department of Anesthesiology, School of Medicine, Loma Linda University, Loma Linda, CA, the United States of America [6]Department of Neurosurgery, School of Medicine, Loma Linda University, Loma Linda, CA, the United States of America [*1]School of Medicine, Loma Linda University, 11041 Campus Street, Loma Linda, CA 92354, the United States of America [*2]Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 China
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