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A meta-analysis of Lactate Ringer's solution versus Normal Saline in the treatment of acute pancreatitis

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资源类型：
Pubmed体系：
作者：
Wang Zhengwang[1] * ; Shi Keru[2] ; Mo Shaojian[2,3] ; Liu Ziang[2] ; Yao Jie[4,*1] ;
单位： [1]Yangzhou University Medical College, Yangzhou, Jiangsu, China [2]Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, 030032, China [3]Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China [4]Department of Hepatobiliary and Pancreatic Surgery, Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, China
出处：
DOI： 10.1016/j.gastrohep.2023.12.007
ISSN：

摘要：
Fluid resuscitation is an important way in the treatment of acute pancreatitis (AP). This meta-analysis aimed to compare the safety and efficacy of Lactate Ringer's solution (LR) and Normal Saline (NS) in the treatment of patients with acute pancreatitis. Searched in PubMed, Web of Science Core Collection (Clarivate), Embase, Cochrane Library, CNKI, China Wanfang, and China VIP database. All randomized controlled clinical trials (RCTs) were identified. 6 studies with 431 patients were included. Compared with NS, LR can significantly reduce the incidence of SIRS at 24 hours, reduce the length of hospitalization, moderate-severe AP, ICU admission and local complications, especially pancreatic necrosis. It is safe and effective to choose LR for fluid resuscitation in AP, but due to the small number of included studies, multi-center and large-sample RCTs are still needed for further verification.Copyright © 2023 Elsevier España, S.L.U. All rights reserved.

语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2022]版：
大类 | 4 区 医学
小类 | 4 区 胃肠肝病学
最新[2025]版：
大类 | 4 区 医学
小类 | 4 区 胃肠肝病学
第一作者：
第一作者单位： [1]Yangzhou University Medical College, Yangzhou, Jiangsu, China
通讯作者：
通讯机构： [4]Department of Hepatobiliary and Pancreatic Surgery, Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, China [*1]Department: Department of Hepatobiliary and Pancreatic Surgery, Clinical Medical College, Yangzhou University Institute/University/Hospital, Yangzhou University, Street Name & Number: No. 98 Nantong West Road, Yangzhou, Jiangsu province, 225009, China
推荐引用方式(GB/T 7714)：
Wang Zhengwang,Shi Keru,Mo Shaojian,et al.A meta-analysis of Lactate Ringer's solution versus Normal Saline in the treatment of acute pancreatitis[J].Gastroenterologia Y Hepatologia.2023,doi:10.1016/j.gastrohep.2023.12.007.
APA：
Wang Zhengwang,Shi Keru,Mo Shaojian,Liu Ziang&Yao Jie.(2023).A meta-analysis of Lactate Ringer's solution versus Normal Saline in the treatment of acute pancreatitis.Gastroenterologia Y Hepatologia,,
MLA：
Wang Zhengwang,et al."A meta-analysis of Lactate Ringer's solution versus Normal Saline in the treatment of acute pancreatitis".Gastroenterologia Y Hepatologia .(2023)

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