单位:[1]Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.华中科技大学同济医学院附属协和医院[2]Division of Cardiology, Hubei Key Laboratory of Genetics and Molecular Mechanisms of Cardiological Disorders, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.内科学系心血管内科华中科技大学同济医学院附属同济医院[3]Department of Paediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.华中科技大学同济医学院附属协和医院[4]Ultrasonic Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.华中科技大学同济医学院附属协和医院[5]Department of Internal Medicine II, University Hospital Würzburg, Julius-Maximilian University of Würzburg, Würzburg, Germany
The 2019 coronavirus disease (COVID-19) patients had a unique profile of gut bacteria. In this study, we characterized the intestinal bacteria in our COVID-19 cohorts and found that there was an increased incidence of severe cases in COVID-19 patients with decreased lymphocytes and increased neutrophils. Levels of lymphocytes and neutrophils and abundances of intestinal bacteria correlated with the severity of COVID-19.
基金:
Department of Science and Technology of Hubei
Province (2020BHB017 and 2020FCA014), the Natural Science Foundation of Hubei
Province (2021CFB450), and the Wuhan Knowledge Innovation Special Basic Research
Project (2022020801010462).
第一作者单位:[1]Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
共同第一作者:
通讯作者:
推荐引用方式(GB/T 7714):
Chen Liuying,Yin Zhongwei,Zhou Dan,et al.Lymphocyte and neutrophil count combined with intestinal bacteria abundance predict the severity of COVID-19[J].MICROBIOLOGY SPECTRUM.2024,12(1):e0302723.doi:10.1128/spectrum.03027-23.
APA:
Chen Liuying,Yin Zhongwei,Zhou Dan,Li Xin,Yu Cheng...&Hou Xiaohua.(2024).Lymphocyte and neutrophil count combined with intestinal bacteria abundance predict the severity of COVID-19.MICROBIOLOGY SPECTRUM,12,(1)
MLA:
Chen Liuying,et al."Lymphocyte and neutrophil count combined with intestinal bacteria abundance predict the severity of COVID-19".MICROBIOLOGY SPECTRUM 12..1(2024):e0302723