Patients with coronavirus disease 2019 (COVID-19) have been shown to die mainly due to disease-induced acute respiratory distress syndrome (ARDS). Prone position ventilation (PPV) is an important ventilation strategy in the management of patients with ARDS.To investigate the application of PPV in ventilation strategies for patients with COVID-19.Three hundred patients with COVID-19 admitted to the Intensive Care Unit (ICU) of Shanxi Bethune Hospital from January 2020 to June 2021 were retrospectively collected. Based on body position and conscious state, all patients were divided into three groups: intubation prone position group (n= 110), awake prone position group (n= 90) and supine position group (n= 100); The acute physiology and chronic health evaluation II (APACHE-II) scores, blood gas indicators, complications and other relevant clinical indicators were compared among the three groups. One-way ANOVA was used to compare means between multiple groups for quantitative information that conformed to a normal distribution. Repeated measures ANOVA was used for repeated measures data. Component comparisons were made using the Kruskal-Wallis H rank sum test for non-normally distributed quantitative data.One-way repeated-measures ANOVA main effect analysis showed different effects of different treatments on PaO2 in patients with COVID-19 (F treatment = 256.231, P< 0.05), with the order of awake prone position group > intubation prone position group > supine position group. The effects of the three different treatments on P/F in patients with COVID-19 (F treatment = 311.661, P< 0.05), with the order of awake prone position group > supine position group > intubation prone position group; Moreover, the three treatments had different effects on APACHE II scores in patients with COVID-19 (F treatment = 201.342, P< 0.05), with the order of intubation prone position group > supine position group > awake prone position group.Intubation prone position and awake prone position can improve lung function to some extent in patients with COVID-19, and should be applied as early as possible in patients with COVID-19-induced ARDS.
基金：
This study was supported by Shanxi Province ‘136 Revitalization Medical Project Construction Funds’
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2022]版：
大类|4 区工程技术
小类|4 区工程：生物医学4 区卫生保健与服务
最新[2025]版：
大类|4 区医学
小类|4 区工程：生物医学4 区卫生保健与服务
第一作者：
第一作者单位：[1]General Surgery Department, Shanxi Bethune Hospital, Taiyuan, Shanxi, China.[2]Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.[3]Vascular Surgery Department, Shanxi Bethune Hospital, Taiyuan, Shanxi, China.
通讯作者：
通讯机构：[1]General Surgery Department, Shanxi Bethune Hospital, Taiyuan, Shanxi, China.[2]Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.[4]Biliary and Pancreatic Surgery, Shanxi Bethune Hospital, Taiyuan, Shanxi, China.[*1]Biliary and Pancreatic Surgery, Shanxi Bethune Hospital, No. 99 Longcheng Street, Taiyuan, Taiyuan, Shanxi 030032, China
推荐引用方式(GB/T 7714)：
Bai Yuan,He Fang,Yu Ying,et al.Application of prone position ventilation in ventilation strategies for patients with COVID-19[J].Technology and health care : official journal of the European Society for Engineering and Medicine.2023,doi:10.3233/THC-230874.
APA：
Bai Yuan,He Fang,Yu Ying&Li Jia.(2023).Application of prone position ventilation in ventilation strategies for patients with COVID-19.Technology and health care : official journal of the European Society for Engineering and Medicine,,
MLA：
Bai Yuan,et al."Application of prone position ventilation in ventilation strategies for patients with COVID-19".Technology and health care : official journal of the European Society for Engineering and Medicine .(2023)
