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O-GlcNAcylation: A Crucial Regulator in Cancer-Associated Biological Events

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收录情况： ◇ SCIE

作者：

单位： [1]Medical College, Three Gorges University, Yichang, 443000, China. [2]Cancer Center, Renmin Hospital of Wuhan University, Wuhan, 430060, China. [3]Guangzhou National Laboratory, Guangzhou, 510005, China. [4]Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China

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关键词： O-GlcNAc OGT Cancer Biological events

摘要：

O-GlcNAcylation, a recently discovered post-translational modification of proteins, plays a crucial role in regulating protein structure and function, and is closely associated with multiple diseases. Research has shown that O-GlcNAcylation is abnormally upregulated in most cancers, promoting disease progression. To elucidate the roles of O-GlcNAcylation in cancer, this review summarizes various cancer-associated biological events regulated by O-GlcNAcylation and the corresponding signaling pathways. This work may provide insights for future studies on the function or underlying mechanisms of O-GlcNAcylation in cancer.© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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出版当年[2022]版：

大类 | 4 区生物学

小类 | 4 区细胞生物学 4 区生物物理 4 区生化与分子生物学

最新[2025]版：

大类 | 4 区生物学

小类 | 4 区生化与分子生物学 4 区生物物理 4 区细胞生物学

JCR分区：

出版当年[2021]版：

Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Q3 BIOPHYSICS Q4 CELL BIOLOGY

最新[2023]版：

Q3 BIOPHYSICS Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Q4 CELL BIOLOGY

影响因子： 1.8 最新[2023版] 2 最新五年平均 2.989 出版当年[2021版] 2.726 出版当年五年平均 2.194 出版前一年[2020版] 2.6 出版后一年[2022版]

第一作者：

第一作者单位： [1]Medical College, Three Gorges University, Yichang, 443000, China. [2]Cancer Center, Renmin Hospital of Wuhan University, Wuhan, 430060, China. [3]Guangzhou National Laboratory, Guangzhou, 510005, China.

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通讯作者：

通讯机构： [2]Cancer Center, Renmin Hospital of Wuhan University, Wuhan, 430060, China. [3]Guangzhou National Laboratory, Guangzhou, 510005, China.

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