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Identifying features and severity of 2019 coronavirus disease (COVID-19) on admission based on thoracic computer tomography

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单位: [1]901st Hosp Joint Logist Support Force PLA, Dept Radiol, Hefei 230031, Peoples R China [2]Wuhan Taikang Tongji Hosp, Dept Radiol, Wuhan 430050, Peoples R China
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关键词: 2019 corona virus disease pneumonia Tomography X-ray compute

摘要:
Background: To investigate the computer tomography (CT) features of 2019 coronavirus disease (COVID-19)-related pneumonia and its value for identifying severity. Material and Methods: Seventy-three patients with COVID-19 were divided into severe and nonsevere groups. CT signs were divided into two states: presence and absence; involvement range was divided into four grades; and affected lobes were divided into two states: >= 3 lobes and < 3 lobes; laboratory indices were divided into two states: normal and abnormal; co-occurrence of signs was divided into three states: ground-glass opacity (GGO) plus consolidation, only GGO, or only consolidation. The numbers of patients were respectively recorded. Statistical analysis was performed through the chi(2) test, followed by multivariate logistic regression analysis. Results: Some indicators differed, including pure GGO (p<0.001), GGO with focal consolidation (p=0.009), patchy consolidation (p=0.004), sheeted consolidation (p<0.001), fibrotic appearance (p=0.020), involvement grade (p<0.001), affected lobes (p=0.027), pleural effusion (p=0.001), subpleural line (p=0.015), crazy paving signs (p<0.001), halo signs (p=0.020), thickened bronchial walls (p<0.001), air bronchi signs (p=0.003), lesions in mid/inner zone (p<0.001), liver function (p=0.044), interleukin-6 (p<0.001), c-reactive protein (p<0.001), lymphocyte count (p<0.001), and age (p=0.036). Pure GGO (OR:30.711, HR:1.292 similar to 729.882, p=0.034) and involvement grade (OR:0.017, HR:0.001 similar to 0.342, p=0.008) were independent risk factors. Conclusion: On admission, CT signs of COVID-19-related pneumonia were diverse but characteristic, and some CT findings may be potential warning factors for severity, while a lack of GGO and extensive pneumonia may be independent risk factors.

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出版当年[2021]版:
大类 | 4 区 医学
小类 | 4 区 核医学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 核医学
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出版当年[2020]版:
Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
最新[2023]版:
Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

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通讯机构: [1]901st Hosp Joint Logist Support Force PLA, Dept Radiol, Hefei 230031, Peoples R China [2]Wuhan Taikang Tongji Hosp, Dept Radiol, Wuhan 430050, Peoples R China
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